BDBM184251 US9150577, 120

SMILES: CN(C)c1cccc(Cn2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cn2)c1

InChI Key: InChIKey=FUSNKBMQTJQAFQ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 2 (Homo sapiens (Human))	BDBM184251 (US9150577, 120) Show SMILES CN(C)c1cccc(Cn2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cn2)c1 Show InChI InChI=1S/C25H26N6O2/c1-29(2)21-6-3-5-17(11-21)15-30-16-20(14-27-30)28-24(32)19-8-7-18-12-23-25(33)26-9-4-10-31(23)22(18)13-19/h3,5-8,11-14,16H,4,9-10,15H2,1-2H3,(H,26,33)(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9150577 (2015) BindingDB Entry DOI: 10.7270/Q2GB22V6
					More data for this Ligand-Target Pair