BDBM18440 4-benzenesulfonamido-N-butylbenzamide::Sulfonamide analogue, 11
SMILES: CCCCNC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1
InChI Key: InChIKey=KAKHSUSGOXHWSK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM18440 (4-benzenesulfonamido-N-butylbenzamide | Sulfonamid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 7.15E+3 | -6.92 | 2.46E+4 | n/a | n/a | n/a | n/a | 5.9 | 21 |
NIH | Assay Description Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss... | Proc Natl Acad Sci U S A 104: 13192-7 (2007) Article DOI: 10.1073/pnas.0705637104 BindingDB Entry DOI: 10.7270/Q2V1232M | |||||||||||
More data for this Ligand-Target Pair |