BDBM184633 US9156810, (62, 63)
SMILES: CCN(CC)C(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\C(O)Cc2cc3ccccc3s2)[C@H](O)C(C)(C)C1=O
InChI Key: InChIKey=YEMANPZYEQIDPU-NBFZGHLFSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human)) | BDBM184633 (US9156810, (62, 63)) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Allergan, Inc. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot... | US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM184633 (US9156810, (62, 63)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 478 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Allergan, Inc. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot... | US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM184633 (US9156810, (62, 63)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 832 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Allergan, Inc. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot... | US Patent US9156810 (2015) BindingDB Entry DOI: 10.7270/Q2PV6J5K | |||||||||||
More data for this Ligand-Target Pair |