BDBM18517 6-(1-Pyrrolidine)quinolin-2(1H)-one, 4b(+/-)::6-(2-methylpyrrolidin-1-yl)-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::rac-6-(2-Methylpyrrolidin-1-yl)-4-trifluoromethyl-1H-quinolin-2-one

SMILES: CC1CCCN1c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key: InChIKey=MJCSHBNDRSZPKR-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM18517 (6-(1-Pyrrolidine)quinolin-2(1H)-one, 4b(+/-) | 6-(...) Show SMILES CC1CCCN1c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F Show InChI InChI=1S/C15H15F3N2O/c1-9-3-2-6-20(9)10-4-5-13-11(7-10)12(15(16,17)18)8-14(21)19-13/h4-5,7-9H,2-3,6H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	72	-10.1	n/a	n/a	13	n/a	n/a	7.4	37
Ligand Pharmaceuticals Inc.					Assay Description The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...				J Med Chem 50: 5049-52 (2007) Article DOI: 10.1021/jm070231h BindingDB Entry DOI: 10.7270/Q29Z935Z
					More data for this Ligand-Target Pair