BDBM18548 7-[(2-methylbut-3-en-2-yl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::alkylamino-2-quinolinone, 9h

SMILES: CC(C)(Nc1ccc2c(cc(=O)[nH]c2c1)C(F)(F)F)C=C

InChI Key: InChIKey=JGCAPFPVSHXPRA-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM18548 (7-[(2-methylbut-3-en-2-yl)amino]-4-(trifluoromethy...) Show SMILES CC(C)(Nc1ccc2c(cc(=O)[nH]c2c1)C(F)(F)F)C=C Show InChI InChI=1S/C15H15F3N2O/c1-4-14(2,3)20-9-5-6-10-11(15(16,17)18)8-13(21)19-12(10)7-9/h4-8,20H,1H2,2-3H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	118	-9.82	122	n/a	n/a	n/a	n/a	7.4	37
Ligand Pharmaceuticals Inc.					Assay Description The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...				Bioorg Med Chem Lett 17: 1523-6 (2007) Article DOI: 10.1016/j.bmcl.2007.01.007 BindingDB Entry DOI: 10.7270/Q22J6950
					More data for this Ligand-Target Pair