null

SMILES: CN(CCSc1ccccc1)C1CCN(CC1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=HTUWAPIXCUXZNH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2/Glutathione S-transferase P (Homo sapiens (Human))	BDBM185596 (US9156856, 6 | US9493431, 6) Show SMILES CN(CCSc1ccccc1)C1CCN(CC1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C38H44ClN5O3S2/c1-41(27-28-48-36-8-3-2-4-9-36)34-19-21-44(22-20-34)49(46,47)40-38(45)31-13-17-35(18-14-31)43-25-23-42(24-26-43)29-32-7-5-6-10-37(32)30-11-15-33(39)16-12-30/h2-18,34H,19-29H2,1H3,(H,40,45)	PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	704	-8.39	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...				US Patent US9493431 (2016) BindingDB Entry DOI: 10.7270/Q2RB73HH
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM185596 (US9156856, 6 | US9493431, 6) Show SMILES CN(CCSc1ccccc1)C1CCN(CC1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C38H44ClN5O3S2/c1-41(27-28-48-36-8-3-2-4-9-36)34-19-21-44(22-20-34)49(46,47)40-38(45)31-13-17-35(18-14-31)43-25-23-42(24-26-43)29-32-7-5-6-10-37(32)30-11-15-33(39)16-12-30/h2-18,34H,19-29H2,1H3,(H,40,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	704	-8.39	n/a	n/a	n/a	n/a	n/a	n/a	25
AbbVie Inc. US Patent					Assay Description Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...				US Patent US9156856 (2015) BindingDB Entry DOI: 10.7270/Q2125RFF
					More data for this Ligand-Target Pair