BDBM185601 US9156856, 11::US9493431, 11

SMILES: CC(=O)Nc1nc(C)c(s1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=FYAQPGHLNLPUGG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-Bcl-2 Protein (Homo sapiens (Human))	BDBM185601 (US9156856, 11 | US9493431, 11) Show SMILES CC(=O)Nc1nc(C)c(s1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C30H30ClN5O4S2/c1-20-29(41-30(32-20)33-21(2)37)42(39,40)34-28(38)23-9-13-26(14-10-23)36-17-15-35(16-18-36)19-24-5-3-4-6-27(24)22-7-11-25(31)12-8-22/h3-14H,15-19H2,1-2H3,(H,34,38)(H,32,33,37)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	177	-9.20	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...				US Patent US9493431 (2016) BindingDB Entry DOI: 10.7270/Q2RB73HH
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM185601 (US9156856, 11 | US9493431, 11) Show SMILES CC(=O)Nc1nc(C)c(s1)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C30H30ClN5O4S2/c1-20-29(41-30(32-20)33-21(2)37)42(39,40)34-28(38)23-9-13-26(14-10-23)36-17-15-35(16-18-36)19-24-5-3-4-6-27(24)22-7-11-25(31)12-8-22/h3-14H,15-19H2,1-2H3,(H,34,38)(H,32,33,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	177	-9.20	n/a	n/a	n/a	n/a	n/a	n/a	25
AbbVie Inc. US Patent					Assay Description Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...				US Patent US9156856 (2015) BindingDB Entry DOI: 10.7270/Q2125RFF
					More data for this Ligand-Target Pair