BDBM185692 UNC10099985::US9156822, 33

SMILES: Clc1cccc(C2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl

InChI Key: InChIKey=HVXBMABYUWVXDA-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185692 (UNC10099985 | US9156822, 33) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C24H28Cl2N2O2/c25-22-5-3-4-20(23(22)26)18-9-13-28(14-10-18)12-1-2-15-30-19-7-6-17-8-11-27-24(29)21(17)16-19/h3-7,16,18H,1-2,8-15H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	20	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185692 (UNC10099985 | US9156822, 33) Show SMILES Clc1cccc(C2CCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C24H28Cl2N2O2/c25-22-5-3-4-20(23(22)26)18-9-13-28(14-10-18)12-1-2-15-30-19-7-6-17-8-11-27-24(29)21(17)16-19/h3-7,16,18H,1-2,8-15H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	64	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair