BDBM185698 UNC10108019::US9156822, 42

SMILES: O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2[nH]1

InChI Key: InChIKey=WKXGCJMHUWZCIC-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185698 (UNC10108019 | US9156822, 42) Show SMILES O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2[nH]1 Show InChI InChI=1S/C25H29N3O4/c29-24-9-7-19-6-8-20(18-21(19)26-24)30-15-2-1-10-27-11-13-28(14-12-27)22-4-3-5-23-25(22)32-17-16-31-23/h3-9,18H,1-2,10-17H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185698 (UNC10108019 | US9156822, 42) Show SMILES O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4OCCOc34)cc2[nH]1 Show InChI InChI=1S/C25H29N3O4/c29-24-9-7-19-6-8-20(18-21(19)26-24)30-15-2-1-10-27-11-13-28(14-12-27)22-4-3-5-23-25(22)32-17-16-31-23/h3-9,18H,1-2,10-17H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.900	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair