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BDBM185776 US9162991, 15h

SMILES: Cc1cccc(\C=C\C(=O)n2nnc3ccccc23)c1

InChI Key: InChIKey=KKWCVPMPVASJKH-MDZDMXLPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185776   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transglutaminases (TGase)


(Cavia cutleri (Guinea pig))
BDBM185776
PNG
(US9162991, 15h)
Show SMILES Cc1cccc(\C=C\C(=O)n2nnc3ccccc23)c1
Show InChI InChI=1S/C16H13N3O/c1-12-5-4-6-13(11-12)9-10-16(20)19-15-8-3-2-7-14(15)17-18-19/h2-11H,1H3/b10-9+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Ottawa

US Patent


Assay Description
For enzymology studies of these compounds, recombinant guinea pig liver TGase was expressed in Escherichia coli and effectively purified (Gillet, S. ...


US Patent US9162991 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X8J
More data for this
Ligand-Target Pair