BDBM185907 US9163007, 414

SMILES: Fc1cccc(CNc2n[nH]c3ccc(cc23)-c2cn(Cc3ccccc3)nn2)c1

InChI Key: InChIKey=SEBKOZFHVGMEEY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 185907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM185907 (US9163007, 414) Show SMILES Fc1cccc(CNc2n[nH]c3ccc(cc23)-c2cn(Cc3ccccc3)nn2)c1 Show InChI InChI=1S/C23H19FN6/c24-19-8-4-7-17(11-19)13-25-23-20-12-18(9-10-21(20)26-28-23)22-15-30(29-27-22)14-16-5-2-1-3-6-16/h1-12,15H,13-14H2,(H2,25,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	38	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description 11 data point. Cdc7 kinase assays were carried out in 25 mM HEPES, pH 7.5, 1 mM DTT, 10 mM MgCl2, 100 μM Na3VO4, and 0.075 mg/ml Triton X-100 u...				US Patent US9163007 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DTG
					More data for this Ligand-Target Pair