BDBM185986 US9163008, 75::US9656968, Compound 75

SMILES: NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1

InChI Key: InChIKey=HICKPJYJOOIJSI-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 185986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185986 (US9163008, 75 | US9656968, Compound 75) Show SMILES NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1 |r| Show InChI InChI=1S/C21H17ClFN5O3/c22-12-3-6-17(14(23)9-12)31-13-4-1-11(2-5-13)20-27-16(19(24)29)10-18(28-20)26-15-7-8-25-21(15)30/h1-6,9-10,15H,7-8H2,(H2,24,29)(H,25,30)(H,26,27,28)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...				US Patent US9656968 (2017) BindingDB Entry DOI: 10.7270/Q2F76FMS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM185986 (US9163008, 75 | US9656968, Compound 75) Show SMILES NC(=O)c1cc(N[C@H]2CCNC2=O)nc(n1)-c1ccc(Oc2ccc(Cl)cc2F)cc1 |r| Show InChI InChI=1S/C21H17ClFN5O3/c22-12-3-6-17(14(23)9-12)31-13-4-1-11(2-5-13)20-27-16(19(24)29)10-18(28-20)26-15-7-8-25-21(15)30/h1-6,9-10,15H,7-8H2,(H2,24,29)(H,25,30)(H,26,27,28)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma, L.P. US Patent					Assay Description In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...				US Patent US9163008 (2015) BindingDB Entry DOI: 10.7270/Q2G44P21
					More data for this Ligand-Target Pair