BDBM186570 US9163040, 2
SMILES: OC(=O)C[C@@H](Cc1ccc(cc1)-c1cc(Cl)ccc1F)NC(=O)CCP(O)(O)=O
InChI Key: InChIKey=TWKJROJSAYIJLA-OAHLLOKOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM186570 (US9163040, 2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | 7.4 | 25 |
NOVARTIS AG US Patent | Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 pM) is pre-incubated wi... | US Patent US9163040 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TV2 | |||||||||||
More data for this Ligand-Target Pair |