BDBM186811 US9670203, Compound 1.3

SMILES: COc1ccc(CNC(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)cc1

InChI Key: InChIKey=XRBFMVHIERTUDE-HJOGWXRNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-Raf (Y340D/Y341D) (Homo sapiens (Human))	BDBM186811 (US9670203, Compound 1.3) Show SMILES COc1ccc(CNC(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)cc1 |r| Show InChI InChI=1S/C26H24N4O5/c1-33-15-4-2-14(3-5-15)13-28-26(32)30-23-22-18-12-16(6-8-19(18)35-24(22)23)34-20-10-11-27-25-17(20)7-9-21(31)29-25/h2-6,8,10-12,22-24H,7,9,13H2,1H3,(H,27,29,31)(H2,28,30,32)/t22-,23-,24-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	25
BeiGene, Ltd. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US9670203 (2017) BindingDB Entry DOI: 10.7270/Q20Z71F5
					More data for this Ligand-Target Pair
B-Raf (V600E) (Homo sapiens (Human))	BDBM186811 (US9670203, Compound 1.3) Show SMILES COc1ccc(CNC(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)cc1 |r| Show InChI InChI=1S/C26H24N4O5/c1-33-15-4-2-14(3-5-15)13-28-26(32)30-23-22-18-12-16(6-8-19(18)35-24(22)23)34-20-10-11-27-25-17(20)7-9-21(31)29-25/h2-6,8,10-12,22-24H,7,9,13H2,1H3,(H,27,29,31)(H2,28,30,32)/t22-,23-,24-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	25
BeiGene, Ltd. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US9670203 (2017) BindingDB Entry DOI: 10.7270/Q20Z71F5
					More data for this Ligand-Target Pair