null

SMILES: COc1ccccc1-c1ccc2NC(C)(C)C=C(CSc3ccc(Cl)cc3)c2c1

InChI Key: InChIKey=DKLYGWOPRPJURQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18714 (4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyp...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSc3ccc(Cl)cc3)c2c1 |t:17| Show InChI InChI=1S/C25H24ClNOS/c1-25(2)15-18(16-29-20-11-9-19(26)10-12-20)22-14-17(8-13-23(22)27-25)21-6-4-5-7-24(21)28-3/h4-15,27H,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18714 (4-{[(4-chlorophenyl)sulfanyl]methyl}-6-(2-methoxyp...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSc3ccc(Cl)cc3)c2c1 |t:17| Show InChI InChI=1S/C25H24ClNOS/c1-25(2)15-18(16-29-20-11-9-19(26)10-12-20)22-14-17(8-13-23(22)27-25)21-6-4-5-7-24(21)28-3/h4-15,27H,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair