BDBM18715 1-({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-yl]methyl}sulfanyl)ethan-1-one::dihydroquinoline compound, 26

SMILES: COc1ccccc1-c1ccc2NC(C)(C)C=C(CSC(C)=O)c2c1

InChI Key: InChIKey=ZIWULKAFQVYSMS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18715 (1-({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroq...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSC(C)=O)c2c1 |t:17| Show InChI InChI=1S/C21H23NO2S/c1-14(23)25-13-16-12-21(2,3)22-19-10-9-15(11-18(16)19)17-7-5-6-8-20(17)24-4/h5-12,22H,13H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18715 (1-({[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroq...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(CSC(C)=O)c2c1 |t:17| Show InChI InChI=1S/C21H23NO2S/c1-14(23)25-13-16-12-21(2,3)22-19-10-9-15(11-18(16)19)17-7-5-6-8-20(17)24-4/h5-12,22H,13H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair