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SMILES: CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1ccccc1F

InChI Key: InChIKey=OSHKIGHNCFPISW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18717 (6-(2-fluorophenyl)-2,2-dimethyl-4-[(prop-2-en-1-yl...) Show SMILES CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1ccccc1F |c:16| Show InChI InChI=1S/C21H22FNS/c1-4-11-24-14-16-13-21(2,3)23-20-10-9-15(12-18(16)20)17-7-5-6-8-19(17)22/h4-10,12-13,23H,1,11,14H2,2-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18717 (6-(2-fluorophenyl)-2,2-dimethyl-4-[(prop-2-en-1-yl...) Show SMILES CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1ccccc1F |c:16| Show InChI InChI=1S/C21H22FNS/c1-4-11-24-14-16-13-21(2,3)23-20-10-9-15(12-18(16)20)17-7-5-6-8-19(17)22/h4-10,12-13,23H,1,11,14H2,2-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair