BDBM18720 2-chloro-3-{2,2-dimethyl-4-[(prop-2-en-1-ylsulfanyl)methyl]-1,2-dihydroquinolin-6-yl}phenol::dihydroquinoline compound, 43

SMILES: CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1cccc(O)c1Cl

InChI Key: InChIKey=AZXWUJXCVIDGJV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18720 (2-chloro-3-{2,2-dimethyl-4-[(prop-2-en-1-ylsulfany...) Show SMILES CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1cccc(O)c1Cl |c:16| Show InChI InChI=1S/C21H22ClNOS/c1-4-10-25-13-15-12-21(2,3)23-18-9-8-14(11-17(15)18)16-6-5-7-19(24)20(16)22/h4-9,11-12,23-24H,1,10,13H2,2-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18720 (2-chloro-3-{2,2-dimethyl-4-[(prop-2-en-1-ylsulfany...) Show SMILES CC1(C)Nc2ccc(cc2C(CSCC=C)=C1)-c1cccc(O)c1Cl |c:16| Show InChI InChI=1S/C21H22ClNOS/c1-4-10-25-13-15-12-21(2,3)23-18-9-8-14(11-17(15)18)16-6-5-7-19(24)20(16)22/h4-9,11-12,23-24H,1,10,13H2,2-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 16: 1549-52 (2006) Article DOI: 10.1016/j.bmcl.2005.12.043 BindingDB Entry DOI: 10.7270/Q25B00RG
					More data for this Ligand-Target Pair