BDBM18729 6-(2-methoxyphenyl)-2,2-dimethyl-4-[2-methyl-1-(prop-2-en-1-yloxy)propyl]-1,2-dihydroquinoline::dihydroquinoline-based ligand, 18

SMILES: COc1ccccc1-c1ccc2NC(C)(C)C=C(C(OCC=C)C(C)C)c2c1

InChI Key: InChIKey=UQGIWZOYDNHCSJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18729 (6-(2-methoxyphenyl)-2,2-dimethyl-4-[2-methyl-1-(pr...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(OCC=C)C(C)C)c2c1 |t:17| Show InChI InChI=1S/C25H31NO2/c1-7-14-28-24(17(2)3)21-16-25(4,5)26-22-13-12-18(15-20(21)22)19-10-8-9-11-23(19)27-6/h7-13,15-17,24,26H,1,14H2,2-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18729 (6-(2-methoxyphenyl)-2,2-dimethyl-4-[2-methyl-1-(pr...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(OCC=C)C(C)C)c2c1 |t:17| Show InChI InChI=1S/C25H31NO2/c1-7-14-28-24(17(2)3)21-16-25(4,5)26-22-13-12-18(15-20(21)22)19-10-8-9-11-23(19)27-6/h7-13,15-17,24,26H,1,14H2,2-6H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair