BDBM18730 6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1-yloxy)butyl]-1,2-dihydroquinoline::dihydroquinoline-based ligand, 19

SMILES: CCCC(OCC=C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC

InChI Key: InChIKey=RIIJLXFIVQWZNO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18730 (6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...) Show SMILES CCCC(OCC=C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC |t:8| Show InChI InChI=1S/C25H31NO2/c1-6-10-24(28-15-7-2)21-17-25(3,4)26-22-14-13-18(16-20(21)22)19-11-8-9-12-23(19)27-5/h7-9,11-14,16-17,24,26H,2,6,10,15H2,1,3-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18730 (6-(2-methoxyphenyl)-2,2-dimethyl-4-[1-(prop-2-en-1...) Show SMILES CCCC(OCC=C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC |t:8| Show InChI InChI=1S/C25H31NO2/c1-6-10-24(28-15-7-2)21-17-25(3,4)26-22-14-13-18(16-20(21)22)19-11-8-9-12-23(19)27-5/h7-9,11-14,16-17,24,26H,2,6,10,15H2,1,3-5H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair