BDBM18734 6-(2-methoxyphenyl)-2,2-dimethyl-4-[3-phenyl-1-(prop-2-en-1-yloxy)propyl]-1,2-dihydroquinoline::dihydroquinoline-based ligand, 23

SMILES: COc1ccccc1-c1ccc2NC(C)(C)C=C(C(CCc3ccccc3)OCC=C)c2c1

InChI Key: InChIKey=KPAXBIAZFPSKKK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18734 (6-(2-methoxyphenyl)-2,2-dimethyl-4-[3-phenyl-1-(pr...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(CCc3ccccc3)OCC=C)c2c1 |t:17| Show InChI InChI=1S/C30H33NO2/c1-5-19-33-29(18-15-22-11-7-6-8-12-22)26-21-30(2,3)31-27-17-16-23(20-25(26)27)24-13-9-10-14-28(24)32-4/h5-14,16-17,20-21,29,31H,1,15,18-19H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18734 (6-(2-methoxyphenyl)-2,2-dimethyl-4-[3-phenyl-1-(pr...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(CCc3ccccc3)OCC=C)c2c1 |t:17| Show InChI InChI=1S/C30H33NO2/c1-5-19-33-29(18-15-22-11-7-6-8-12-22)26-21-30(2,3)31-27-17-16-23(20-25(26)27)24-13-9-10-14-28(24)32-4/h5-14,16-17,20-21,29,31H,1,15,18-19H2,2-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair