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SMILES: O=C(c1nnc(o1)N1CC[C@@H](C1)OCc1ccccc1)c1nc2ccc(cc2s1)-c1ccccc1

InChI Key: InChIKey=LVOJLNVUNVFARK-NRFANRHFSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187342   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM187342
PNG
(US9169240, 81)
Show SMILES O=C(c1nnc(o1)N1CC[C@@H](C1)OCc1ccccc1)c1nc2ccc(cc2s1)-c1ccccc1 |r|
Show InChI InChI=1S/C27H22N4O3S/c32-24(26-28-22-12-11-20(15-23(22)35-26)19-9-5-2-6-10-19)25-29-30-27(34-25)31-14-13-21(16-31)33-17-18-7-3-1-4-8-18/h1-12,15,21H,13-14,16-17H2/t21-/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 490n/an/an/an/a8.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...

US Patent US9169240 (2015)


BindingDB Entry DOI: 10.7270/Q2W66JK8
More data for this
Ligand-Target Pair