BDBM18735 4-(1-methoxyethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline::dihydroquinoline-based ligand, 24

SMILES: COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC

InChI Key: InChIKey=UKWDXTKCAKQGJP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18735 (4-(1-methoxyethyl)-6-(2-methoxyphenyl)-2,2-dimethy...) Show SMILES COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC |t:4| Show InChI InChI=1S/C21H25NO2/c1-14(23-4)18-13-21(2,3)22-19-11-10-15(12-17(18)19)16-8-6-7-9-20(16)24-5/h6-14,22H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18735 (4-(1-methoxyethyl)-6-(2-methoxyphenyl)-2,2-dimethy...) Show SMILES COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC |t:4| Show InChI InChI=1S/C21H25NO2/c1-14(23-4)18-13-21(2,3)22-19-11-10-15(12-17(18)19)16-8-6-7-9-20(16)24-5/h6-14,22H,1-5H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair