BDBM18736 4-{1-[(2E)-but-2-en-1-yloxy]ethyl}-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline::dihydroquinoline-based ligand, 25

SMILES: COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OC\C=C\C)c2c1

InChI Key: InChIKey=JFEUWHWUEKXKKU-VOTSOKGWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18736 (4-{1-[(2E)-but-2-en-1-yloxy]ethyl}-6-(2-methoxyphe...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OC\C=C\C)c2c1 |t:17| Show InChI InChI=1S/C24H29NO2/c1-6-7-14-27-17(2)21-16-24(3,4)25-22-13-12-18(15-20(21)22)19-10-8-9-11-23(19)26-5/h6-13,15-17,25H,14H2,1-5H3/b7-6+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18736 (4-{1-[(2E)-but-2-en-1-yloxy]ethyl}-6-(2-methoxyphe...) Show SMILES COc1ccccc1-c1ccc2NC(C)(C)C=C(C(C)OC\C=C\C)c2c1 |t:17| Show InChI InChI=1S/C24H29NO2/c1-6-7-14-27-17(2)21-16-24(3,4)25-22-13-12-18(15-20(21)22)19-10-8-9-11-23(19)26-5/h6-13,15-17,25H,14H2,1-5H3/b7-6+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair