BDBM18737 6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(3-methylbut-2-en-1-yl)oxy]ethyl}-1,2-dihydroquinoline::dihydroquinoline-based ligand, 26

SMILES: [#6]-[#8]-c1ccccc1-c1ccc2-[#7]C([#6])([#6])[#6]=[#6](-[#6](-[#6])-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])-c2c1

InChI Key: InChIKey=DQALECYZLFPXOQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18737 (6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(3-methylbu...) Show SMILES [#6]-[#8]-c1ccccc1-c1ccc2-[#7]C([#6])([#6])[#6]=[#6](-[#6](-[#6])-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])-c2c1 |t:17| Show InChI InChI=1S/C25H31NO2/c1-17(2)13-14-28-18(3)22-16-25(4,5)26-23-12-11-19(15-21(22)23)20-9-7-8-10-24(20)27-6/h7-13,15-16,18,26H,14H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18737 (6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(3-methylbu...) Show SMILES [#6]-[#8]-c1ccccc1-c1ccc2-[#7]C([#6])([#6])[#6]=[#6](-[#6](-[#6])-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])-c2c1 |t:17| Show InChI InChI=1S/C25H31NO2/c1-17(2)13-14-28-18(3)22-16-25(4,5)26-23-12-11-19(15-21(22)23)20-9-7-8-10-24(20)27-6/h7-13,15-16,18,26H,14H2,1-6H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	395	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair