BDBM18738 6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(2E)-pent-2-en-1-yloxy]ethyl}-1,2-dihydroquinoline::dihydroquinoline-based ligand, 27

SMILES: CC\C=C\COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC

InChI Key: InChIKey=BNKAEHGIVAYNSJ-JXMROGBWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18738 (6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(2E)-pent-2...) Show SMILES CC\C=C\COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC |t:8| Show InChI InChI=1S/C25H31NO2/c1-6-7-10-15-28-18(2)22-17-25(3,4)26-23-14-13-19(16-21(22)23)20-11-8-9-12-24(20)27-5/h7-14,16-18,26H,6,15H2,1-5H3/b10-7+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18738 (6-(2-methoxyphenyl)-2,2-dimethyl-4-{1-[(2E)-pent-2...) Show SMILES CC\C=C\COC(C)C1=CC(C)(C)Nc2ccc(cc12)-c1ccccc1OC |t:8| Show InChI InChI=1S/C25H31NO2/c1-6-7-10-15-28-18(2)22-17-25(3,4)26-23-14-13-19(16-21(22)23)20-11-8-9-12-24(20)27-5/h7-14,16-18,26H,6,15H2,1-5H3/b10-7+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	565	n/a	n/a	n/a	n/a	7.4	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description IC50 values shown are means of a single experiment done in duplicate 11-point concentration-effect curves.				Bioorg Med Chem Lett 17: 5091-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.021 BindingDB Entry DOI: 10.7270/Q21J981M
					More data for this Ligand-Target Pair