null

SMILES: CC[C@H](Nc1ncnc(N)c1-c1ncc(C)o1)c1nc2cccc(Cl)c2c(=O)n1C1CC1

InChI Key: InChIKey=UTGBAOBFAHYEMU-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 188325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform (Homo sapiens (Human))	BDBM188325 (US9670194, Ex. 7 (S)-2-(1-((6-amino-5-(5-methyloxa...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1ncc(C)o1)c1nc2cccc(Cl)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C22H22ClN7O2/c1-3-14(28-19-17(18(24)26-10-27-19)21-25-9-11(2)32-21)20-29-15-6-4-5-13(23)16(15)22(31)30(20)12-7-8-12/h4-6,9-10,12,14H,3,7-8H2,1-2H3,(H3,24,26,27,28)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	246	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...				US Patent US9670194 (2017) BindingDB Entry DOI: 10.7270/Q2NS0S1D
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM188325 (US9670194, Ex. 7 (S)-2-(1-((6-amino-5-(5-methyloxa...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1ncc(C)o1)c1nc2cccc(Cl)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C22H22ClN7O2/c1-3-14(28-19-17(18(24)26-10-27-19)21-25-9-11(2)32-21)20-29-15-6-4-5-13(23)16(15)22(31)30(20)12-7-8-12/h4-6,9-10,12,14H,3,7-8H2,1-2H3,(H3,24,26,27,28)/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110β/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4,5-bisphosphate and MgATP (concentration as ...				US Patent US9670194 (2017) BindingDB Entry DOI: 10.7270/Q2NS0S1D
					More data for this Ligand-Target Pair