BDBM188449 US9169224, 138

SMILES: O=C(Nc1ccccc1)N1CCN(Cc2cccc(OS(=O)(=O)c3ccccc3)c2)CC1

InChI Key: InChIKey=FACBXOHFYSYKNJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM188449 (US9169224, 138) Show SMILES O=C(Nc1ccccc1)N1CCN(Cc2cccc(OS(=O)(=O)c3ccccc3)c2)CC1 Show InChI InChI=1S/C24H25N3O4S/c28-24(25-21-9-3-1-4-10-21)27-16-14-26(15-17-27)19-20-8-7-11-22(18-20)31-32(29,30)23-12-5-2-6-13-23/h1-13,18H,14-17,19H2,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	9.0	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....				US Patent US9169224 (2015) BindingDB Entry DOI: 10.7270/Q24Q7ST1
					More data for this Ligand-Target Pair