BDBM18904 2-[3,5-dibromo-4-(cyclohexylmethoxy)phenyl]acetic acid::3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9g

SMILES: OC(=O)Cc1cc(Br)c(OCC2CCCCC2)c(Br)c1

InChI Key: InChIKey=BNBWGVDBRHRJFJ-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM18904 (2-[3,5-dibromo-4-(cyclohexylmethoxy)phenyl]acetic ...) Show SMILES OC(=O)Cc1cc(Br)c(OCC2CCCCC2)c(Br)c1 Show InChI InChI=1S/C15H18Br2O3/c16-12-6-11(8-14(18)19)7-13(17)15(12)20-9-10-4-2-1-3-5-10/h6-7,10H,1-5,8-9H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	0.420	n/a	n/a	7.0	4
Karo Bio AB					Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to...				J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM18904 (2-[3,5-dibromo-4-(cyclohexylmethoxy)phenyl]acetic ...) Show SMILES OC(=O)Cc1cc(Br)c(OCC2CCCCC2)c(Br)c1 Show InChI InChI=1S/C15H18Br2O3/c16-12-6-11(8-14(18)19)7-13(17)15(12)20-9-10-4-2-1-3-5-10/h6-7,10H,1-5,8-9H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	776	n/a	n/a	n/a	n/a	n/a	n/a
University of Insubria Curated by ChEMBL					Assay Description Inhibition of human thyroid hormone receptor beta 1				Bioorg Med Chem 15: 5251-61 (2007) Article DOI: 10.1016/j.bmc.2007.05.016 BindingDB Entry DOI: 10.7270/Q2PK0HD8
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM18904 (2-[3,5-dibromo-4-(cyclohexylmethoxy)phenyl]acetic ...) Show SMILES OC(=O)Cc1cc(Br)c(OCC2CCCCC2)c(Br)c1 Show InChI InChI=1S/C15H18Br2O3/c16-12-6-11(8-14(18)19)7-13(17)15(12)20-9-10-4-2-1-3-5-10/h6-7,10H,1-5,8-9H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	770	n/a	0.520	n/a	n/a	7.0	4
Karo Bio AB					Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i...				J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW
					More data for this Ligand-Target Pair