BDBM189304 US9670194, Ex. 32 (S)-2-(1-((6-amino-5-(1-methyl-1H-1,2,4-triazol-3-yl)pyrimidin-4-yl)amino)-propyl)-5-chloro-3-phenylquinazolin-4(3H)-one

SMILES: CC[C@H](Nc1ncnc(N)c1-c1ncn(C)n1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1

InChI Key: InChIKey=GOIZRJDAHAOHMH-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110δ/p85α (Homo sapiens (Human))	BDBM189304 (US9670194, Ex. 32 (S)-2-(1-((6-amino-5-(1-methyl-1...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1ncn(C)n1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C24H22ClN9O/c1-3-16(30-21-19(20(26)27-12-28-21)22-29-13-33(2)32-22)23-31-17-11-7-10-15(25)18(17)24(35)34(23)14-8-5-4-6-9-14/h4-13,16H,3H2,1-2H3,(H3,26,27,28,30)/t16-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...				US Patent US9670194 (2017) BindingDB Entry DOI: 10.7270/Q2NS0S1D
					More data for this Ligand-Target Pair