BDBM1894 1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiourea::CHEMBL33981::LY73497::N-(2-phenethyl)-N -(2-thiazolyl)thiourea::Phenylethylthiazolylthiourea (PETT) Analog

SMILES: S=C(NCCc1ccccc1)Nc1nccs1

InChI Key: InChIKey=ANUSGJXVCFPWMQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM1894 (1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiourea | CHE...) Show SMILES S=C(NCCc1ccccc1)Nc1nccs1 Show InChI InChI=1S/C12H13N3S2/c16-11(15-12-14-8-9-17-12)13-7-6-10-4-2-1-3-5-10/h1-5,8-9H,6-7H2,(H2,13,14,15,16)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 38: 4929-36 (1995) Article DOI: 10.1021/jm00025a010 BindingDB Entry DOI: 10.7270/Q2639MXG
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM1894 (1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiourea | CHE...) Show SMILES S=C(NCCc1ccccc1)Nc1nccs1 Show InChI InChI=1S/C12H13N3S2/c16-11(15-12-14-8-9-17-12)13-7-6-10-4-2-1-3-5-10/h1-5,8-9H,6-7H2,(H2,13,14,15,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Post Graduate Department of Chemistry, Sree Chaitanya College, Habra, 24 Parganas 743268, India. Electronic address: debasisdas@chemconfidence.com. Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase using and rCdC as template and tritium-labeled dGTP incubated for 30 mins by liquid scintillation counting ...				Eur J Med Chem 109: 89-98 (2016) BindingDB Entry DOI: 10.7270/Q2PC347J
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM1894 (1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiourea | CHE...) Show SMILES S=C(NCCc1ccccc1)Nc1nccs1 Show InChI InChI=1S/C12H13N3S2/c16-11(15-12-14-8-9-17-12)13-7-6-10-4-2-1-3-5-10/h1-5,8-9H,6-7H2,(H2,13,14,15,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Medivir AB Curated by ChEMBL					Assay Description Antiviral activity was determined against HIV- 1 reverse transcriptase				Bioorg Med Chem Lett 8: 1511-6 (1999) BindingDB Entry DOI: 10.7270/Q2RR1XDZ
					More data for this Ligand-Target Pair