BindingDB logo
myBDB logout

null

SMILES: CCc1nc(no1)-c1c(N)ncnc1N[C@@H](C)c1nc2cccc(Cl)c2c(=O)n1C1CC1

InChI Key: InChIKey=MRZSSZGDKDBNFF-JTQLQIEISA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189842   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform


(Homo sapiens (Human))		BDBM189842
PNG
(US9670194, Ex. 61 (S)-2-(1-((6-amino-5-(5-ethyl-1,...)
Show SMILES CCc1nc(no1)-c1c(N)ncnc1N[C@@H](C)c1nc2cccc(Cl)c2c(=O)n1C1CC1 |r|
Show InChI InChI=1S/C21H21ClN8O2/c1-3-14-28-19(29-32-14)16-17(23)24-9-25-18(16)26-10(2)20-27-13-6-4-5-12(22)15(13)21(31)30(20)11-7-8-11/h4-6,9-11H,3,7-8H2,1-2H3,(H3,23,24,25,26)/t10-/m0/s1
UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 44n/an/an/an/an/a25



CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...

US Patent US9670194 (2017)


BindingDB Entry DOI: 10.7270/Q2NS0S1D
More data for this
Ligand-Target Pair