BDBM189971 US9175003, 112

SMILES: OC(=O)[C@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)NC(=O)[C@@H]1Cc2cc3OCC(Oc3cc2CN1S(=O)(=O)c1ccc(nc1)N1CCOCC1)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=IOFIDDARNLKUOU-HXCLOYEWSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (GLP-1) (Homo sapiens (Human))	BDBM189971 (US9175003, 112) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)NC(=O)[C@@H]1Cc2cc3OCC(Oc3cc2CN1S(=O)(=O)c1ccc(nc1)N1CCOCC1)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 |r| Show InChI InChI=1S/C50H43Cl2N5O9S/c51-41-15-5-33(21-42(41)52)29-64-39-12-10-36(11-13-39)47-30-65-45-24-37-23-44(49(58)55-43(50(59)60)22-31-1-6-34(7-2-31)35-8-3-32(26-53)4-9-35)57(28-38(37)25-46(45)66-47)67(61,62)40-14-16-48(54-27-40)56-17-19-63-20-18-56/h1-16,21,24-25,27,43-44,47H,17-20,22-23,28-30H2,(H,55,58)(H,59,60)/t43-,44-,47?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...				US Patent US9175003 (2015) BindingDB Entry DOI: 10.7270/Q27943FG
					More data for this Ligand-Target Pair