BDBM190250 US9175357, 5599

SMILES: CNC(=O)c1cc(-c2ccccc2)n(c1C)-c1ccccc1

InChI Key: InChIKey=KSOTYGSPFVAQRD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM190250 (US9175357, 5599) Show SMILES CNC(=O)c1cc(-c2ccccc2)n(c1C)-c1ccccc1 |w:1.0| Show InChI InChI=1S/C19H18N2O/c1-14-17(19(22)20-2)13-18(15-9-5-3-6-10-15)21(14)16-11-7-4-8-12-16/h3-13H,1-2H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	8.0	25
UNIVERSITY OF SOUTH CAROLINA US Patent					Assay Description The buffer composition was 50 mM Tris, 200 mM NaCl, 2.0 mM DTT, and 0.005% Tween 20 (pH 8.0). Fragment ligated inhibitors and comparison peptides to ...				US Patent US9175357 (2015) BindingDB Entry DOI: 10.7270/Q2V40T14
					More data for this Ligand-Target Pair