null
SMILES: CCNC(=O)c1ccc(Nc2nc3ccc(cn3n2)N2CCN(CC2)C(=O)NCc2ccc(F)cc2)c(OCC)c1
InChI Key: InChIKey=QAWXRRKDKVZDDV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM190356 (US9670202, Example01.01 4-(2-{[2-ethoxy-4-(ethylca...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | 7.7 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9670202 (2017) BindingDB Entry DOI: 10.7270/Q24Q7S5H | |||||||||||
More data for this Ligand-Target Pair |