null

SMILES: NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cc2)C#N)cc1

InChI Key: InChIKey=PZSJUVFXYLWILL-UXHICEINSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 190553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM190553 (US9181185, 30g | US9624194, Compound 30g) Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cc2)C#N)cc1 |r| Show InChI InChI=1S/C21H17N3O4/c22-12-13-4-8-15(9-5-13)28-16-10-6-14(7-11-16)17-2-1-3-18(24-17)19(25)20(26)21(23)27/h1-11,19-20,25-26H,(H2,23,27)/t19-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...				US Patent US9624194 (2017) BindingDB Entry DOI: 10.7270/Q2BP04VG
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM190553 (US9181185, 30g | US9624194, Compound 30g) Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cccc(n1)-c1ccc(Oc2ccc(cc2)C#N)cc1 |r| Show InChI InChI=1S/C21H17N3O4/c22-12-13-4-8-15(9-5-13)28-16-10-6-14(7-11-16)17-2-1-3-18(24-17)19(25)20(26)21(23)27/h1-11,19-20,25-26H,(H2,23,27)/t19-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	37
Purdue Pharma L.P. US Patent					Assay Description FLIPR® or FLIPRTETRA® Sodium Dye Assay with KCl and Test Article Pre-Incubation: Cells were prepared by plating the recombinant HEK293 cells or other...				US Patent US9181185 (2015) BindingDB Entry DOI: 10.7270/Q2PC315D
					More data for this Ligand-Target Pair