null

SMILES: NC(=O)[C@@H](O)[C@H](O)c1cn(-c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)c2ccccc12

InChI Key: InChIKey=LGQCXQLQZDVWKA-RTWAWAEBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 190558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM190558 (US9181185, 8 | US9624194, Compound 8) Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cn(-c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)c2ccccc12 Show InChI InChI=1S/C23H18F3N3O4/c24-23(25,26)13-5-10-19(28-11-13)33-15-8-6-14(7-9-15)29-12-17(20(30)21(31)22(27)32)16-3-1-2-4-18(16)29/h1-12,20-21,30-31H,(H2,27,32)/t20-,21+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...				US Patent US9624194 (2017) BindingDB Entry DOI: 10.7270/Q2BP04VG
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM190558 (US9181185, 8 | US9624194, Compound 8) Show SMILES NC(=O)[C@@H](O)[C@H](O)c1cn(-c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)c2ccccc12 Show InChI InChI=1S/C23H18F3N3O4/c24-23(25,26)13-5-10-19(28-11-13)33-15-8-6-14(7-9-15)29-12-17(20(30)21(31)22(27)32)16-3-1-2-4-18(16)29/h1-12,20-21,30-31H,(H2,27,32)/t20-,21+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	37
Purdue Pharma L.P. US Patent					Assay Description FLIPR® or FLIPRTETRA® Sodium Dye Assay with KCl and Test Article Pre-Incubation: Cells were prepared by plating the recombinant HEK293 cells or other...				US Patent US9181185 (2015) BindingDB Entry DOI: 10.7270/Q2PC315D
					More data for this Ligand-Target Pair