BDBM191057 US9181253, 119
SMILES: O[C@H]1C[C@]2(C[C@H]2[C@H]1O)n1cnc2c(NCC3CC3)nc(Cl)nc12
InChI Key: InChIKey=VDWGKCZTRLYCCA-WKGDZTOBSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM191057 (US9181253, 119) | GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.90 | -11.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Radioligand binding assays at A1, A2A, and A3ARs were performed according to the procedures described previously. Each tube in the binding assay cont... | US Patent US9181253 (2015) BindingDB Entry DOI: 10.7270/Q2CV4GJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM191057 (US9181253, 119) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 68.4 | -9.77 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Radioligand binding assays at A1, A2A, and A3ARs were performed according to the procedures described previously. Each tube in the binding assay cont... | US Patent US9181253 (2015) BindingDB Entry DOI: 10.7270/Q2CV4GJ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM191057 (US9181253, 119) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.41E+3 | -7.30 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
The United States of America, as represented by the Secretary, Department of Health and Human Services US Patent | Assay Description Radioligand binding assays at A1, A2A, and A3ARs were performed according to the procedures described previously. Each tube in the binding assay cont... | US Patent US9181253 (2015) BindingDB Entry DOI: 10.7270/Q2CV4GJ4 | |||||||||||
More data for this Ligand-Target Pair |