BDBM191117 US9181258, 112

SMILES: NCC[C@H]1CNC(=O)c2cc(c(-c3ccc4OCOc4c3)n12)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=XSIPCMUZGAGULD-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM191117 (US9181258, 112) Show SMILES NCC[C@H]1CNC(=O)c2cc(c(-c3ccc4OCOc4c3)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H20F3N3O4/c24-23(25,26)33-16-3-1-2-13(8-16)17-10-18-22(30)28-11-15(6-7-27)29(18)21(17)14-4-5-19-20(9-14)32-12-31-19/h1-5,8-10,15H,6-7,11-12,27H2,(H,28,30)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191117 (US9181258, 112) Show SMILES NCC[C@H]1CNC(=O)c2cc(c(-c3ccc4OCOc4c3)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H20F3N3O4/c24-23(25,26)33-16-3-1-2-13(8-16)17-10-18-22(30)28-11-15(6-7-27)29(18)21(17)14-4-5-19-20(9-14)32-12-31-19/h1-5,8-10,15H,6-7,11-12,27H2,(H,28,30)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair