null

SMILES: CCS(=O)(=O)NC1CCCc2c1cncc2-c1ccc(cc1)C#N

InChI Key: InChIKey=ZSJBVCOSEKPJCV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191877 (US9187429, 2) Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1ccc(cc1)C#N Show InChI InChI=1S/C18H19N3O2S/c1-2-24(22,23)21-18-5-3-4-15-16(11-20-12-17(15)18)14-8-6-13(10-19)7-9-14/h6-9,11-12,18,21H,2-5H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	207	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191877 (US9187429, 2) Show SMILES CCS(=O)(=O)NC1CCCc2c1cncc2-c1ccc(cc1)C#N Show InChI InChI=1S/C18H19N3O2S/c1-2-24(22,23)21-18-5-3-4-15-16(11-20-12-17(15)18)14-8-6-13(10-19)7-9-14/h6-9,11-12,18,21H,2-5H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair