BDBM191923 US9187429, 64::US9187429, 65::US9187429, 66

SMILES: CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=IDQNXHUBIRPFEM-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 191923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191923 (US9187429, 64 | US9187429, 65 | US9187429, 66) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O2S/c1-2-25(23,24)22-16-8-7-13-14(9-21-10-15(13)16)11-3-5-12(6-4-11)17(18,19)20/h3-6,9-10,16,22H,2,7-8H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191923 (US9187429, 64 | US9187429, 65 | US9187429, 66) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O2S/c1-2-25(23,24)22-16-8-7-13-14(9-21-10-15(13)16)11-3-5-12(6-4-11)17(18,19)20/h3-6,9-10,16,22H,2,7-8H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191923 (US9187429, 64 | US9187429, 65 | US9187429, 66) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O2S/c1-2-25(23,24)22-16-8-7-13-14(9-21-10-15(13)16)11-3-5-12(6-4-11)17(18,19)20/h3-6,9-10,16,22H,2,7-8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191923 (US9187429, 64 | US9187429, 65 | US9187429, 66) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O2S/c1-2-25(23,24)22-16-8-7-13-14(9-21-10-15(13)16)11-3-5-12(6-4-11)17(18,19)20/h3-6,9-10,16,22H,2,7-8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	730	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191923 (US9187429, 64 | US9187429, 65 | US9187429, 66) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O2S/c1-2-25(23,24)22-16-8-7-13-14(9-21-10-15(13)16)11-3-5-12(6-4-11)17(18,19)20/h3-6,9-10,16,22H,2,7-8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191923 (US9187429, 64 | US9187429, 65 | US9187429, 66) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O2S/c1-2-25(23,24)22-16-8-7-13-14(9-21-10-15(13)16)11-3-5-12(6-4-11)17(18,19)20/h3-6,9-10,16,22H,2,7-8H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair