BDBM191929 US9187429, 71::US9187429, 72::US9187429, 73

SMILES: CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(c(F)c1)C(F)(F)F

InChI Key: InChIKey=VGSMPCYZNBSZII-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 191929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191929 (US9187429, 71 | US9187429, 72 | US9187429, 73) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N2O2S/c1-2-26(24,25)23-16-6-4-11-12(8-22-9-13(11)16)10-3-5-14(15(18)7-10)17(19,20)21/h3,5,7-9,16,23H,2,4,6H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191929 (US9187429, 71 | US9187429, 72 | US9187429, 73) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N2O2S/c1-2-26(24,25)23-16-6-4-11-12(8-22-9-13(11)16)10-3-5-14(15(18)7-10)17(19,20)21/h3,5,7-9,16,23H,2,4,6H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191929 (US9187429, 71 | US9187429, 72 | US9187429, 73) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N2O2S/c1-2-26(24,25)23-16-6-4-11-12(8-22-9-13(11)16)10-3-5-14(15(18)7-10)17(19,20)21/h3,5,7-9,16,23H,2,4,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	44.4	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191929 (US9187429, 71 | US9187429, 72 | US9187429, 73) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N2O2S/c1-2-26(24,25)23-16-6-4-11-12(8-22-9-13(11)16)10-3-5-14(15(18)7-10)17(19,20)21/h3,5,7-9,16,23H,2,4,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191929 (US9187429, 71 | US9187429, 72 | US9187429, 73) Show SMILES CCS(=O)(=O)NC1CCc2c1cncc2-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C17H16F4N2O2S/c1-2-26(24,25)23-16-6-4-11-12(8-22-9-13(11)16)10-3-5-14(15(18)7-10)17(19,20)21/h3,5,7-9,16,23H,2,4,6H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	242	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair