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SMILES: CS(=O)(=O)N[C@@H]1CCCc2c1cncc2-c1ccc(cc1F)C(F)(F)F

InChI Key: InChIKey=ARZLMRPAMZHXBV-MRXNPFEDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191933 (US9187429, 76) Show SMILES CS(=O)(=O)N[C@@H]1CCCc2c1cncc2-c1ccc(cc1F)C(F)(F)F |r| Show InChI InChI=1S/C17H16F4N2O2S/c1-26(24,25)23-16-4-2-3-11-13(8-22-9-14(11)16)12-6-5-10(7-15(12)18)17(19,20)21/h5-9,16,23H,2-4H2,1H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	119	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191933 (US9187429, 76) Show SMILES CS(=O)(=O)N[C@@H]1CCCc2c1cncc2-c1ccc(cc1F)C(F)(F)F |r| Show InChI InChI=1S/C17H16F4N2O2S/c1-26(24,25)23-16-4-2-3-11-13(8-22-9-14(11)16)12-6-5-10(7-15(12)18)17(19,20)21/h5-9,16,23H,2-4H2,1H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.32E+4	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair