BDBM191942 US9187429, 85::US9187429, 86

SMILES: CC1(C)Cc2c(cncc2-c2ccc(cc2)C(F)(F)F)C1O

InChI Key: InChIKey=ILCQCLQCKDWTCY-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 191942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191942 (US9187429, 85 | US9187429, 86) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(cc2)C(F)(F)F)C1O Show InChI InChI=1S/C17H16F3NO/c1-16(2)7-12-13(8-21-9-14(12)15(16)22)10-3-5-11(6-4-10)17(18,19)20/h3-6,8-9,15,22H,7H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191942 (US9187429, 85 | US9187429, 86) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(cc2)C(F)(F)F)C1O Show InChI InChI=1S/C17H16F3NO/c1-16(2)7-12-13(8-21-9-14(12)15(16)22)10-3-5-11(6-4-10)17(18,19)20/h3-6,8-9,15,22H,7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	30.4	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191942 (US9187429, 85 | US9187429, 86) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(cc2)C(F)(F)F)C1O Show InChI InChI=1S/C17H16F3NO/c1-16(2)7-12-13(8-21-9-14(12)15(16)22)10-3-5-11(6-4-10)17(18,19)20/h3-6,8-9,15,22H,7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	15.2	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191942 (US9187429, 85 | US9187429, 86) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(cc2)C(F)(F)F)C1O Show InChI InChI=1S/C17H16F3NO/c1-16(2)7-12-13(8-21-9-14(12)15(16)22)10-3-5-11(6-4-10)17(18,19)20/h3-6,8-9,15,22H,7H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair