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SMILES: Fc1cc(ccc1C(F)(F)F)-c1cncc2C(CCc12)NS(=O)(=O)C1CC1

InChI Key: InChIKey=AVMITHMUKZOUSW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191946 (US9187429, 91) Show SMILES Fc1cc(ccc1C(F)(F)F)-c1cncc2C(CCc12)NS(=O)(=O)C1CC1 Show InChI InChI=1S/C18H16F4N2O2S/c19-16-7-10(1-5-15(16)18(20,21)22)13-8-23-9-14-12(13)4-6-17(14)24-27(25,26)11-2-3-11/h1,5,7-9,11,17,24H,2-4,6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	301	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191946 (US9187429, 91) Show SMILES Fc1cc(ccc1C(F)(F)F)-c1cncc2C(CCc12)NS(=O)(=O)C1CC1 Show InChI InChI=1S/C18H16F4N2O2S/c19-16-7-10(1-5-15(16)18(20,21)22)13-8-23-9-14-12(13)4-6-17(14)24-27(25,26)11-2-3-11/h1,5,7-9,11,17,24H,2-4,6H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	389	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair