null

SMILES: NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=KVWWQRRDKCLZMY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191948 (US9187429, 93) Show SMILES NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H13F3N2/c16-15(17,18)10-3-1-9(2-4-10)12-7-20-8-13-11(12)5-6-14(13)19/h1-4,7-8,14H,5-6,19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	86.3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191948 (US9187429, 93) Show SMILES NC1CCc2c1cncc2-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H13F3N2/c16-15(17,18)10-3-1-9(2-4-10)12-7-20-8-13-11(12)5-6-14(13)19/h1-4,7-8,14H,5-6,19H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	364	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair