BDBM191962 US9187429, 108::US9187429, 109

SMILES: CC1(C)Cc2c(cncc2-c2ccc(c(F)c2)C(F)(F)F)C1O

InChI Key: InChIKey=NSJPFIVMVWXUKY-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 191962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191962 (US9187429, 108 | US9187429, 109) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(c(F)c2)C(F)(F)F)C1O Show InChI InChI=1S/C17H15F4NO/c1-16(2)6-10-11(7-22-8-12(10)15(16)23)9-3-4-13(14(18)5-9)17(19,20)21/h3-5,7-8,15,23H,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	304	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191962 (US9187429, 108 | US9187429, 109) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(c(F)c2)C(F)(F)F)C1O Show InChI InChI=1S/C17H15F4NO/c1-16(2)6-10-11(7-22-8-12(10)15(16)23)9-3-4-13(14(18)5-9)17(19,20)21/h3-5,7-8,15,23H,6H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	30.3	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM191962 (US9187429, 108 | US9187429, 109) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(c(F)c2)C(F)(F)F)C1O Show InChI InChI=1S/C17H15F4NO/c1-16(2)6-10-11(7-22-8-12(10)15(16)23)9-3-4-13(14(18)5-9)17(19,20)21/h3-5,7-8,15,23H,6H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM191962 (US9187429, 108 | US9187429, 109) Show SMILES CC1(C)Cc2c(cncc2-c2ccc(c(F)c2)C(F)(F)F)C1O Show InChI InChI=1S/C17H15F4NO/c1-16(2)6-10-11(7-22-8-12(10)15(16)23)9-3-4-13(14(18)5-9)17(19,20)21/h3-5,7-8,15,23H,6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	792	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally derived from a renal leiomyoblastoma. The expression plasmids contains the ORF ...				US Patent US9187429 (2015) BindingDB Entry DOI: 10.7270/Q2668C04
					More data for this Ligand-Target Pair