BDBM192049 Inz-40

SMILES: CCOc1cccc(c1)-c1nn(CC(=O)OC)c2ccccc12

InChI Key: InChIKey=HQHAXNGNOAZIRV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome b (Candida albicans (Yeast))	BDBM192049 (Inz-40) Show SMILES CCOc1cccc(c1)-c1nn(CC(=O)OC)c2ccccc12 Show InChI InChI=1S/C18H18N2O3/c1-3-23-14-8-6-7-13(11-14)18-15-9-4-5-10-16(15)20(19-18)12-17(21)22-2/h4-11H,3,12H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	982	n/a	n/a	n/a	n/a	7.4	25
Massachusetts Institute of Technology					Assay Description The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...				Cell Chem Biol 23: 978-991 (2016) Article DOI: 10.1016/j.chembiol.2016.06.016 BindingDB Entry DOI: 10.7270/Q2SX6C1B
					More data for this Ligand-Target Pair
Cytochrome b (Homo sapiens (Human))	BDBM192049 (Inz-40) Show SMILES CCOc1cccc(c1)-c1nn(CC(=O)OC)c2ccccc12 Show InChI InChI=1S/C18H18N2O3/c1-3-23-14-8-6-7-13(11-14)18-15-9-4-5-10-16(15)20(19-18)12-17(21)22-2/h4-11H,3,12H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a	7.4	25
Massachusetts Institute of Technology					Assay Description The cytochrome b enzyme assay was adapted from previous studies (Gutierrez-Cirlos et al., 2004). Briefly, compounds were diluted in a 23 reaction buf...				Cell Chem Biol 23: 978-991 (2016) Article DOI: 10.1016/j.chembiol.2016.06.016 BindingDB Entry DOI: 10.7270/Q2SX6C1B
					More data for this Ligand-Target Pair