BDBM192298 US9187450, 45::US9321747, 19

SMILES: CC1(C)C[C@H](O)c2c(C1)nc(C1CCN(CC1)c1ncc(OCCCS(C)(=O)=O)cn1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCC(F)(F)CC1

InChI Key: InChIKey=PBBIETQWWVEHHA-ZQAZVOLISA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 192298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM192298 (US9187450, 45 | US9321747, 19) Show SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCN(CC1)c1ncc(OCCCS(C)(=O)=O)cn1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCC(F)(F)CC1 |r| Show InChI InChI=1S/C38H46F6N4O4S/c1-36(2)19-28-31(29(49)20-36)30(23-9-13-37(40,41)14-10-23)32(33(39)24-5-7-26(8-6-24)38(42,43)44)34(47-28)25-11-15-48(16-12-25)35-45-21-27(22-46-35)52-17-4-18-53(3,50)51/h5-8,21-23,25,29,33,49H,4,9-20H2,1-3H3/t29-,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	37
Daiichi Sankyo Company, Limited US Patent					Assay Description A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 ug) and 5,5'...				US Patent US9187450 (2015) BindingDB Entry DOI: 10.7270/Q29022KM
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM192298 (US9187450, 45 | US9321747, 19) Show SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCN(CC1)c1ncc(OCCCS(C)(=O)=O)cn1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCC(F)(F)CC1 |r| Show InChI InChI=1S/C38H46F6N4O4S/c1-36(2)19-28-31(29(49)20-36)30(23-9-13-37(40,41)14-10-23)32(33(39)24-5-7-26(8-6-24)38(42,43)44)34(47-28)25-11-15-48(16-12-25)35-45-21-27(22-46-35)52-17-4-18-53(3,50)51/h5-8,21-23,25,29,33,49H,4,9-20H2,1-3H3/t29-,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	22.9	n/a	n/a	n/a	n/a	n/a	37
DAIICHI SANKYO COMPANY, LIMITED; UBE INDUSTRIES, LTD. US Patent					Assay Description A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 μg) and 5,5...				US Patent US9321747 (2016) BindingDB Entry DOI: 10.7270/Q2TB15S8
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM192298 (US9187450, 45 | US9321747, 19) Show SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCN(CC1)c1ncc(OCCCS(C)(=O)=O)cn1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCC(F)(F)CC1 |r| Show InChI InChI=1S/C38H46F6N4O4S/c1-36(2)19-28-31(29(49)20-36)30(23-9-13-37(40,41)14-10-23)32(33(39)24-5-7-26(8-6-24)38(42,43)44)34(47-28)25-11-15-48(16-12-25)35-45-21-27(22-46-35)52-17-4-18-53(3,50)51/h5-8,21-23,25,29,33,49H,4,9-20H2,1-3H3/t29-,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18.9	n/a	n/a	n/a	n/a	n/a	37
DAIICHI SANKYO COMPANY, LIMITED; UBE INDUSTRIES, LTD. US Patent					Assay Description A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 μg) and 5,5...				US Patent US9321747 (2016) BindingDB Entry DOI: 10.7270/Q2TB15S8
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM192298 (US9187450, 45 | US9321747, 19) Show SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCN(CC1)c1ncc(OCCCS(C)(=O)=O)cn1)c([C@@H](F)c1ccc(cc1)C(F)(F)F)c2C1CCC(F)(F)CC1 |r| Show InChI InChI=1S/C38H46F6N4O4S/c1-36(2)19-28-31(29(49)20-36)30(23-9-13-37(40,41)14-10-23)32(33(39)24-5-7-26(8-6-24)38(42,43)44)34(47-28)25-11-15-48(16-12-25)35-45-21-27(22-46-35)52-17-4-18-53(3,50)51/h5-8,21-23,25,29,33,49H,4,9-20H2,1-3H3/t29-,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	37
DAIICHI SANKYO COMPANY, LIMITED; UBE INDUSTRIES, LTD. US Patent					Assay Description A recombinant human CETP protein (manufactured by Roar Biomedical Inc.; 4.5 ng), the acceptor lipoprotein described in (2) above (32.5 μg) and 5,5...				US Patent US9321747 (2016) BindingDB Entry DOI: 10.7270/Q2TB15S8
					More data for this Ligand-Target Pair