BDBM192495 US9187469, 19

SMILES: CC(C)(C)n1cc(cn1)[C@@H](O)C1CCCN(C1)c1nnnc2cc(ccc12)N1CCOCC1

InChI Key: InChIKey=BABRBUIWGWWIHG-UGNFMNBCSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM192495 (US9187469, 19) Show SMILES CC(C)(C)n1cc(cn1)[C@@H](O)C1CCCN(C1)c1nnnc2cc(ccc12)N1CCOCC1 |r| Show InChI InChI=1S/C24H33N7O2/c1-24(2,3)31-16-18(14-25-31)22(32)17-5-4-8-30(15-17)23-20-7-6-19(13-21(20)26-28-27-23)29-9-11-33-12-10-29/h6-7,13-14,16-17,22,32H,4-5,8-12,15H2,1-3H3/t17?,22-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9187469 (2015) BindingDB Entry DOI: 10.7270/Q2S1819K
					More data for this Ligand-Target Pair